Objective Pseudoephedrine is a stimulant that can be purchased over-the-counter to relieve symptoms of nasal and sinus congestion. Ask questions about drugs that you already typed into duckduckgo. The negative physical effects one might feel will depend on the dosage. Pseudoephedrine abuse, addiction, and dependence are becoming more common, probably due in part to the fact that it is a widely available drug. Use DXM only syrup for recreational purpose and start at lower doses, and work your way up. The main disadvantages are difficulty urinating on high doses and difficulty falling asleep afterwards. Pseudoephedrine is closely related in structure to methamphetamine, although its CNS actions are much less potent and also longer-acting than those of the amphetamines. Pseudoephedrine works by narrowing the blood vessels in your nose, but it also narrows the blood vessels in other parts of your body. Dosage Forms & Strengths ephedrine/guaifenesin tablet 12.5mg/200mg (Primatene Tablets) 25mg/400mg (Bronkaid Dual Action Formula) Asthma Indicated for temporary relief of mild symptoms of intermittent asthma Because of this, Pseudoephedrine is heavily regulated in most parts of the world, either being stored behind the counter, or completely banned. One should be The 4 isomers are classified as true ephedrine or pseudoephedrine, depending on the way their chemical structures are rotated around their centers []. The average dose is 20-40mg which is a very small ammount. DOSAGE AND ADMINISTRATION Adults The usual parenteral dose is 25 to 50 mg given subcutaneously or intramuscularly. While these drugs are very similar, even belonging to the same amphetamine chemical classes, there are distinct differences between them. I've looked and don't any many other options that don't contain other ingredients. Sudafed (pseudoephedrine) is a decongestant that shrinks blood vessels in the nasal passages. Pseudoephedrine is almost the same as ephedrine, weaker though. Please see the citation formatting guide if you need assistance properly formatting citations. It’s an amphetamine and has stimulating effects. If I use it several days in a row, sleep can become impossible even if I only use 120 mg per day. Jun 25, 2006 #9 For most people, 50mg of ephedrine is a nice dose for stimulant purposes, so that translates to 200mg of pseudo. As with other stimulants, the chronic use of pseudoephedrine can be considered moderately addictive and is capable of causing psychological dependence among certain users. Dosage – The dosage, or the amount of the drug, often increases so the user can get the same high as before. Detailed Chlorpheniramine / Dihydrocodeine / Pseudoephedrine dosage information for adults and children. Pseudoephedrine naturally occurs in the plant Ephedra, which contains both Talk:Ephedrine and Pseudoephedrine. Dilated blood vessels can cause nasal congestion Is the optimal dosage for pseudoephedrine as a stimulant the same as the recommended dosage on the packaging for use as a decongestant, or is it safe to go higher? Another sign that someone is abusing this You can help by expanding it. I think nobody has still given the poor fellow the dosage that should be taken for the recreational purpose. WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. My nasal passages were completely cleared up, my body was 100% comfortable, I felt relaxed and yet super alert. There may be an unpleasant withdrawal afterwards, which involves feeling worse emotionally and movement feeling tense and somewhat unpleasant. Pseudoephedrine is a diastereomer of ephedrine and is readily reduced into methamphetamine or oxidized into methcathinone. Pseudoephedrine abuse is not the same as addiction. In response to the issue of misuse of pseudoephedrine-containing products, many companies are voluntarily re-formulating their products to exclude phenylpropanolamine, ephedrine, and pseudoephedrine. Press question mark to learn the rest of the keyboard shortcuts. At higher doses, there can be rushes, but I have the choice to not act speedy but instead be very calm and very perceptive in the present moment. The only side effect was when I took another dose later in the day, I felt uncomfortably warm. Lethal dosage Tolerance and addiction potential As with other stimulants, the chronic use of pseudoephedrine can be considered moderately addictive and is capable of causing psychological dependence among certain users. But what makes Meth make you high, is how it connects to the fatty tissues in your brain and excites neural activity. Abuse means that you are taking excessively large doses of the drug to experience an effect, which is the aim of recreational use. Ephedrine and pseudoephedrine differ in their appearance, their uses, and the way they affect the body. As such, it may contain incomplete or even dangerously wrong information. My nasal passages were completely cleared up, my body was 100% comfortable, I felt relaxed and yet super alert. It may be used as a nasal/sinus decongestant, as a stimulant, or as a wakefulness-promoting agent in higher doses. Detailed Chlorpheniramine / Methscopolamine / Pseudoephedrine dosage information for adults and children. As such, it may contain incomplete or invalid information. However, the pseudoephedrine found in most pharmaceutical products is not derived from plant matter, but instead is. Last updated on February 21, 2020. You can help by expanding it. As for the It is strongly recommended that one use harm reduction practices when using this substance. Pseudoephedrine is used as a precursor to methamphetamine, and is commonly reffered to as "pseudo". But ephedrine is nearly impossible to get nowadays. This can increase your blood pressure and your heart rate. In your opinion, would pseudoephedrine be an overall good stimulant? It is not a recommendation and should be verified with other sources for accuracy. Generic Name: pseudoephedrine (SOO doe ee FED rin) Brand names: Chlor Trimeton Nasal Decongestant, Contac Cold, Drixoral Decongestant Non-Drowsy, Elixsure Decongestant, Entex, Genaphed, Kid Kare Drops, Nasofed, Seudotabs, Silfedrine, Sudafed, Sudafed 12-Hour, Sudafed 24-Hour, Sudafed Children's Nasal Decongestant, Sudodrin, SudoGest, SudoGest 12 Hour, Suphedrin, … I also get an elevated emotional state, and movement feels easy and flowing. I wouldn't call it recreational but ephedrine and pseudoephedrine are ok study aids. Pseudoephedrine Dosage. Ephedrine and pseudoephedrine are phenethylamine derivatives identical in their molecular formula but slightly different in their arrangement of molecules. Dosage Reviews 3.5 Stars Menu Everyday Health Drugs Pseudoephedrine (Sudafed) Reviews Pseudoephedrine (Sudafed) Reviews 7 people have … About Sierra Tucson: Founded over 30 years ago, Sierra Tucson is a leading provider of mental health and substance abuse care. It is more euphoric too. Applies to the following strengths: 7.5 mg/0.8 mL; 30 mg; 120 mg; 15 mg/5 mL; 60 mg; 15 mg; 240 mg; 30 mg/5 mL; 50 mg/5 mL; 22.5 mg/5 mL. Is there any known negative effects/health problems associated with long-term daily pseudoephedrine usage that won't go away when usage is discontinued? Detailed Doxylamine / Pseudoephedrine dosage information for adults and children. Essentially, pseudoephedrine occurs naturally along with other ephedrine-related compounds in certain plants. I don't think it's a particularly good stimulant. The clinical dose is 2 tablets (60 mg) over the course of 4 hours. For me, the main advantage are certain uplifting emotional effects which don't seem typical for stimulants. Likewise, adverse effects become much more likely with higher doses and may include serious injury or death. I'm surprised you felt anything but decongestant effects at 30mg. I was taking 60mg of PE (2x 30mg in each pill), not sure if that is still too little to feel an effect, maybe the stimulant/euphoric feeling was just a placebo. This page was last modified on 16 June 2020, at 06:17. This page has not been approved by the PsychonautWiki administrators. Pseudoephedrine is used over-the-counter as a nasal decongestant, which is usually combined with other medications such as NSAID's, acetaminophen, dextromethorphan, guaifenesin and various antihistamines. Dosage Overdose What to avoid Side effects Interactions FAQ What is Sudafed? Subjectively, I'd put eph + caffiene on about the same level as a 3-5mg dose of addy. Wal-Mart and the like have generic versions of sudafed that are far cheaper. Not sure how concentrated the ephedra/ephedrine is in it, so I might read up on "mormon tea" a bit and consider giving that a try. As such, it is still in progress and may contain incomplete or wrong information. Pseudoephedrine has had a controversial history in sports, as some athletes have used it as a performance-enhanci… This notice will be removed once this draft has been approved for publication by an administrator. Ephenidine has been described as a designer drug. It's probably a bad idea to take it every day. Intravenously, 5 to 25 mg may be administered slowly, repeated in 5 to 10 minutes, if necessary. Pseudoephedrine is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes. Learn about dosage, side effects, warnings, and why Sudafed is kept behind the counter instead of on the pharmacy shelf. Loss of control – This refers to a person’s inability to reduce or control his or her pseudoephedrine use. Pseudo is .25x as strong an effect (on the CNS) as ephedrine. 3 oz., but not important)one should be marked at 1.5oz, use tape on the outside to mark it (you might want to label it as ether). This History and culture section is a stub. Includes dosages for Cough and Nasal Congestion; plus renal, liver and dialysis adjustments. I'm surprised that 30mg had a notable effect, but I can feel 60 mg, and even after having used it on plenty of occasions, 120 mg is pretty strong but not pushy. First off, not talking about using it to make meth or anything, just taking pure pseudoephedrine. Pseudoephedrine primary mechanism of action is through increasing catecholamine activity at alpha, beta-1, and beta-2 adrenergic receptors. Both are considered sympathomimetic drugs, which means that they affect the sympathetic nervous system. Would the body develop a tolerance similar to caffeine or nicotine or will the same dose continue to be as effective? Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), a literature based on anecdotal reports and the personal experiences of PsychonautWiki contributors. Would the body develop a tolerance similar to caffeine or nicotine or will the same dose continue to be as effective? Pseudoephedrine is sometimes abused, or used for non-medical purposes, because of its stimulant effects - it can give an excitable, hyperactive feeling and increase heart rate and blood pressure. This section is used to both host drafts for unpublished articles, as well as discussions for published ones. Walmart's brand is probably least expensive. Owing to … This dangerous interactions section is a stub. Pseudoephedrine is a diastereomer of ephedrine. Designer drugs are substances mimic the functional and structural features of commonly used illicit substances in order to circumvent government regulation. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Pseudoephedrine is a substituted amphetamine and a structural methamphetamine analogue. Additional experience reports can be found here: This toxicity and harm potential section is a stub. You can help by expanding or correcting it.We also recommend that you conduct independent research and use harm reduction practices when using this substance. Would the body develop a tolerance similar to caffeine or I'm surprised you felt anything but decongestant effects at 30mg. Pseudoephedrine is nice for recreational use. If you'd like to use this area to discuss this draft, please do so in the 'Discussion' section at the very bottom of the page. At Bluelight.org we encourage collaborative partnerships between academic researchers and our community. You can help by expanding or correcting it. Sudafed Congestion 30 mg., 72 Tablets This Item is Only Available for Purchase at your Local Costco WarehouseNon-DrowsyPseudoephedrine HCl 30 mg.Maximum Strength Sinus Congestion ReliefAvailable Behind the Pharmacy Priapism 161 GUIDELINES ON PRIAPISM (Text update March 2015) A. Salonia, I. Eardley, F. Giuliano, I. Moncada, K. Hatzimouratidis Eur Urol 2014 Feb;65(2):480-9 Introduction Priapism is a pathological condition representing a Fast forward... at one point I was out of allergy medications and decided out of desperation one day to try Advil Cold & Flu which is 200 mg ibuprofen, 30 mg pseudoephedrine hydrochloride (I take 2 at once as directed so double that)... that stuff is magic. The FDA approved DXM in 19… My first few experiences were most impressive. I feel relaxed and very comfortable with my body. . DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. Erowid Experience Vaults: Pseudoephedrine, https://psychonautwiki.org/w/index.php?title=Talk:Pseudoephedrine&oldid=141889, Creative Commons Attribution-ShareAlike 4.0 International. Pseudoephedrine presents cross-tolerance with other dopaminergic stimulants, meaning that after the consumption of pseudoephedrine, most other stimulant compounds will have a reduced effect. This article is in the 'Talk' namespace because it is an unfinished draft. I've used up to 360 mg. That makes it pushy and during some portions of the experience pleasantly rushy, but other positive aspects don't improve very much between 120 and 360 mg. New comments cannot be posted and votes cannot be cast. I get similar effects. The drug has a low risk of dependence, however, and withdrawal symptoms are unlikely to develop after stopping the drug. As a result, they should be treated with a healthy amount of skepticism. It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. Includes dosages for Cough and Nasal Congestion; plus renal, liver and dialysis adjustments. There are currently no anecdotal reports which describe the effects of this compound within our experience index. If applicable, a brief paragraph summary of the substance's cognitive effects may be included here. Would you go as far as to consider it a nootropic? Seems a bit expensive though. The maximum recreational As a result, it may contain incomplete or wrong information. See responsible use section. Tolerance to the effects of pseudoephedrine are quickly built after repeated and frequent usage. Anyway in addition to wanting to take it as a decongestant, I've been reading a lot about Adderall lately and feel like I could use a stimulant to help me get through the day, but don't want to go to the doctor's and try and get a prescription (plus more expensive), so I was wondering if maybe pseudoephedrine would be decent OTC substitute, Is Sudafed the only brand of pure pseudoephedrine out there? Dosage Forms: oral liquid (2.5 mg/5 mL); oral tablet (10 mg); oral tablet, chewable, extended release (tannate 10 mg); oral tablet, disintegrating (10 mg) Medically reviewed by … There is definitely some tolerance, and perhaps even long term tolerance after not taking it for almost a year. I am susceptible to side effects, so I have to be very careful about my dosages. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Thanks, looks like I can find Ephedra sinica (Ma huang) powder online for about £15 ($25) for 100g. I also don't think it's a nootropic because it seems like there a bit of mental fog while on it. The racemic parent compound racemorphan was first described in a Swiss and US patent application from Hoffmann-La Roche in 1946 and 1947, respectively; a patent was granted in 1950. Is the optimal dosage for pseudoephedrine as a stimulant the same as the recommended dosage on the packaging for use as a decongestant, or is it safe to go higher? This means that while they are made of the same elements, the 2 molecules differ in the arrangement at 2 molecular centers [ 10 ]. Medically reviewed by Drugs.com. It doesn't effect blood pressure and the intensity of your heartbeat as much as ephedrine does. Its peripheral stimulant actions are similar to but less powerful than those of epinephrine (adrenaline), a hormone produced in the body by the adrenal glands. For most people, 50mg of ephedrine is a nice dose for stimulant purposes, so that translates to 200mg of pseudo. I've tried Allegra (Fexofenadine), Claritin (Loratadine), Benadryl, Cetirizine, you name it... still sneezing and stuffed up after taking each for several weeks at a time. Even when I'm not congested, breathing becomes easier on pseudoephedrine. As such, it may contain incomplete or wrong information. Press J to jump to the feed. List of equipment : • A glass eyedropper • Three small glass bottles with lids (approx. You can help by expanding upon or correcting it. It is worth noting that these effects will not necessarily occur in a consistent or reliable manner, although higher doses are more likely to induce the full spectrum of effects. If you have any heart problems or you're worried about this, speak to a pharmacist or doctor about a different treatment. Includes dosages for Allergic Rhinitis, Nasal Congestion and Sinus Symptoms; plus renal, liver and dialysis adjustments. You may select from a list of cognitive effects to add below. Sudafed is a popular decongestant that’s available at most pharmacies. So if you took enough, and thinned the It's still good though. A resolution of the two isomers of racemorphan with tartaric acid was published in 1952, and DXM was successfully tested in 1954 as part of US Navy and CIA-funded research on nonaddictive substitutes for codeine. You’re not wrong in theory. One might feel will depend on the CNS ) as ephedrine pseudoephedrine recreational dosage should be treated with a healthy of... 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