ImmunoMet Therapeutics is a development-stage biopharmaceutical company focused on the development and commercialization of novel oncology products that are aimed to improve the quality of life of cancer patients. Checkmate-548 was the most recent hope for Opdivo in glioblastoma following the failures, in 2017 and 2019 respectively, of Checkmate-143 in the second-line setting and Checkmate-498 in first-line. Find More Contacts for Immunic Therapeutics, Edit Lists Featuring This Company Section, Immunic, Inc. The company believes this approach may harness the bodys immune system to recognize, attack and destroy tumor cells that express CMV, which is over-expressed in GBM. We believe that these early clinical studies may provide a proof of concept for UNITE in cancer, and if successful, set the stage for future studies, including combinations in these tumor types and others. ROCKVILLE, Md.--(BUSINESS WIRE)--Immunomic Therapeutics, Inc., (ITI), a privately-held clinical-stage biotechnology company pioneering the study of LAMP (Lysosome Associated Membrane Protein)-mediated nucleic acid-based immunotherapy, today announced the appointment of Frances Harrison as Senior Vice President, Regulatory Affairs. To ensure the most secure and best overall experience on our website, we recommend the latest versions of. Immunomic Therapeutics - Products, Competitors, Financials, Employees While research is the essential engine that drives our technology forward, our efforts in process development, manufacturing management, and regulatory affairs are critical factors that advance the Immunomic Therapeutics vision. Jan 30, 2015. ImmunoMet Therapeutics is a biopharmaceutical company that develops and commercializes oncology products for cancer patients. 2015 Mar 19;519(7543):366-9. Home - Immunomic Therapeutics ITI granted Japanese animal health company, ZENOAQ (Nippon Zenyaku Kogyo Co., Ltd, Koriyama, Japan) an exclusive license to develop and commercialize its investigational DNA vaccine for canine atopic dermatitis and other companion animal allergies. Immunomic Therapeutics Announces Presentation on Nucleic Acid-Based Stock ticker symbol (e.g. Find your private company bowl on Fishbowl, join the hottest conversation with your colleagues anonymously. mcarey@rxir.com ITI is primarily focused on applying the UNITE platform to oncology, where it could potentially have broad applications, including antigen-derived antibodies as biologics. Developer of lysosomal-associated membrane protein (LAMP)-based vaccines designed to use immunotherapy to treat cancer, allergies, and animal health. April 23, 2020 04:00 PM Eastern Daylight Time. ITI granted Japanese animal health company, ZENOAQ (Nippon Zenyaku Kogyo Co., Ltd, Koriyama, Japan) an exclusive license to develop and commercialize its investigational DNA vaccine for canine atopic dermatitis and other companion animal allergies. ITI-1001 represents an off-the-shelf cancer immunotherapy approach that leverages ITIs proprietary UNITE platform to target CMV-associated antigens (pp65, IE-1 & gB) in Newly-Diagnosed Glioblastoma Multiforme (GBM).The primary mechanism of action of ITI-1001 is to enable specific presentation of the antigens via the lysosome mediated pathway in the antigen presenting cells (APC). William Hearl - President & CEO - Immunomic Therapeutics, Inc Our goal is to overcome the limitations of current immuno-oncology therapies by . 28 Employees . Clin Cancer Res 2020;26:5297303, Batich K.A.,Long-term Survival in Glioblastoma with Cytomegalovirus pp65-Targeted Vaccination. The Immunomic Therapeutics, Inc. team includes specialists in the areas of science, process development, engineering, production, marketing, finance, human resources, quality and regulatory, administrative support and more. Immunomic Therapeutics is a development stage biotechnology company that develops lysosomal associated membrane protein-based vaccines. Immunomic Therapeutics, Inc. announced today that it has assumed sponsorship of the Investigational New Drug (IND) application for ITI-1000 from the University of Florida (UF). Mitchell D.A.,Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. mkemp@immunomix.com ITI-3000 Merkel Cell Carcinoma - pDNA. Immunic Therapeutics - Crunchbase Company Profile & Funding IMU-935, a selective inverse agonist of the transcription factor RORt, is targeted for development in psoriasis, castration-resistant prostate cancer and Guillain-Barr syndrome. Description. UNITE is a groundbreaking approach to vaccine development that has been applied to create vaccine candidates for rabies, yellow fever, dengue fever, hepatitis C and SARS, a relative to the SARS-CoV-2 coronavirus. Our portfolio includes more than 150 disruptive companies in areas ranging from the life sciences to engineering technology and digital health. Contact Email info@immunomet.com. ITI Company: IMU-856, which targets the restoration of the intestinal barrier function, is targeted for development in diseases involving bowel barrier dysfunction. Innovative Cellular Therapeutics (ICT) is a clinical-stage, VC-backed cell therapy company based in Rockville, MD. We know that there are multiple aspects that inform our platform's success. ITIs investigational UNITE platform, or UNiversal Intracellular Targeted Expression, works by fusing pathogenic antigens with the Lysosomal Associated Membrane Protein, an endogenous protein in humans, for immune processing. Rockville's Immunomic Therapeutics Inc. is on track to go public later this year, after Covid-19 threw a wrench in the vaccine maker's initial timeline. Claim your Free Employer Profile. In addition to TH1 response, we also observe antigen specific antibodies indicative of TH2 response further enhancing the anti-tumor potential of this vaccine.ITI-1001 presents an alternative for patients that missed the treatment window for other therapies or that cannot produce enough cells to start cell therapy manufacturing (~30% of patients). Melissa Kemp 2003 Sep 26;278(39):37926-36. immunomic therapeutics crunchbase - xarxacatala.cat Immunomic Therapeutics, Inc. (ITI) is a privately held, clinical stage biotechnology company pioneering the development of vaccines through its proprietary technology platform, UNiversal Intracellular Targeted Expression (UNITE), which is designed to utilize the bodys natural biochemistry to develop vaccines that generate broad immune responses. Prior to that, Mr. Stamper held positions of increasing responsibility in various operational areas at Lonza Pharmaceuticals and Biotechnology, AstraZeneca Biologics and Eli Lilly & Company. Immunomic Therapeutics Stock Price, Funding, Valuation, Revenue ITI believes that these early clinical studies may provide a proof of concept for UNITE therapy in cancer, and if successful, set the stage for future studies, including combinations in these tumor types and others. To demonstrate our dedication to patients and our understanding of the importance of clinical trials, we have created a . As a result, a robust T cell response by both CD4+ and CD8+ T cells is expected to drive antitumor activity of this product. amy@juniper-point.com Hum Vaccin Immunother. Founded Date 2015. aanagnostou@immunomix.com Mohan Karkada - Director of Research and Development - LinkedIn Amy Conrad Sampson and Mitchell in the development of a new approach to attack Glioblastoma Multiforme (GBM). Join to follow . While induction of tumor-reactive CD8+ T cells is a major goal of cancer therapy, CD4+ T cells provide essential support to CD8+ T cells by promoting their expression of cytotoxic effector molecules and increasing their migratory capacity. Vaccine technology developed at Johns Hopkins could lead to - Hub We have significant capabilities in molecular biology, including nucleic acid vaccine design, immunology, and tumor mouse modeling. Immunomic Therapeutics nucleic acid vaccines have the potential to utilize the bodys natural biochemistry to develop a broad immune response including antibody production, cytokine release and critical immunological memory. 301-968-3501 This is the Immunomic Therapeutics company profile. Immunomic Therapeutics Announces the Appointment of Frances Harrison as ITI-3000 Merkel Cell Carcinoma - pDNA. ITI-1000 is being tested in a randomized, blinded, and placebo-controlled phase 2 study in patients with newly-diagnosed glioblastoma (GBM) that is anticipated to close in 2022. Immunomic Therapeutics, Inc. (ITI) is a privately-held clinical stage biotechnology company revolutionizing the study of the Lysosomal Associated Membrane . While the presence of the CMV pp65 antigen itself is expected to induce a general effector T cell response, fusion of the antigen to Lysosomal Associated Membrane Protein (LAMP) is intended to compel processing of the antigen through a pathway that presents antigens specifically to CD4+ T cells and results in a robust Th1- type response (Arruda, 2006). CONTACT US. Pancreatic cancer is the fourth-most-common cause of cancer-related mortality in the USA. Immunic is a clinical-stage biopharmaceutical company with a pipeline of selective oral immunology therapies focused on treating chronic inflammatory and autoimmune diseases. Melody Carey It is one of the few malignancies for which incidence approximates prevalence, as patients almost always . Stemming from our UNITE Platform, Immunomic Therapeutics has developed a robust and deep pipeline focused on immunotherapeutics with an emphasis in treating and preventing many oncology indications by leveraging specific characteristics of a type of antigen. Immunomic Therapeutics - Overview, News & Competitors | ZoomInfo.com Company profile page for Immunomic Therapeutics Inc including stock price, company news, press releases, executives, board members, and contact information Of special note are the following publications: To browse the literature, please see the curated list at PubMed. Coordinates: 245831.9N 1213154.0E. What is health insurance like at Immunomic Therapeutics. Immunomic Therapeutics is a biotech company committed to patients. San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. ImmunoMet Therapeutics - Crunchbase Company Profile & Funding If you enjoy the challenge that goes naturally with being part of a high growth company, then a career with Immunomic Therapeutics may be just for you. Immunomic Therapeutics (ITI) is a clinical stage biotechnology company pioneering investigational technologies that have the potential to alter how immunotherapy is used for cancer, allergies, and animal health. ITI-3000 is being tested in a Phase 1, open label, First in Human (FIH) study to evaluate the safety, tolerability, and immunogenicity of 4 mg of ITI-3000 in patients with Merkel polyomavirus-positive Merkel cell carcinoma (MCC). Email credentials to careers@immunomix.com. 2020 Immunomic Therapeutics, Inc. All Rights Reserved. ITI-1001 GBM - pDNA. Jan 2006 - Present17 years 2 months. 2017 Jun 12:1-10. ITI-3000 is a plasmid DNA vaccine targeting the large T antigen (LT) of Merkel cell polyomavirus (MCPyV). The Company has built a pipeline leveraging UNITE with programs in oncology, animal health, infectious disease, and allergy. Great people . Immunomic Therapeutics - Crunchbase Company Profile & Funding
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